Journal Of Pediatric Vaccination

Real-world Impact of Rotavirus Vaccination
Patel, Manish M. MSc, MD*; Steele, Duncan PhD†; Gentsch, Jon R. PhD*; Wecker, John PhD†; Glass, Roger I. MD, PhD*; Parashar, Umesh D. MB BS, MPH*
germ Information
From the *National Center for Immunization and Respiratory affections, Centers for Disease discipline and Prevention, Atlanta, GA; and †PATH, Seattle, WA.

The findings and conclusions in this report are those of the authors and do non necessarily represent the views of the Centers for Disease Control and Prevention (CDC). This cla consumption did receive clearance through the appropriate channels at the CDC prior to submission.
Address for correspondence: Manish M. Patel, MSc, MD, Viral Gastroenteritis Section, MS-A47, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333. E-mail: Aul3@CDC.GOV.
manhoodwide, diarrhea is the second most(prenominal) common cause of fatal childhood disease, estimated to cause close to 1.34 million deaths among children aged <5 years.1 Rotavirus is the leading cause of ascetical diarrhea in young children and is responsible for approximately triad of all diarrheal deaths.



2 Two effective rotavirus vaccines, a single-strain washed-out human rotavirus vaccine (Rotarix, GlaxoSmithKline Biologicals) and a multistrain bovine-human reassortant vaccine (RotaTeq, Merck and Company), are right off available and recommended for routine immunization of all infants by the World Health Organization (WHO).3 Efficacy of these vaccines has ranged from 80% to 98% in industrialized countries,47 including Latin America, and 39% to 77% in developing countries, such as Africa and Asia.810 On the nates of faculty data from Europe and America, the WHO initially approved use of the vaccines in these regions in 2006 and within 2 years some(prenominal) countries added rotavirus vaccination into their routine immunization programs. Subsequently, after proof of efficacy in Asia and Africa, the WHO recommendation was expanded to all infants worldwide in...If you postulate to get a full essay, order it on our website: Orderessay



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